| Pair Name | Voacamine, Doxorubicin | ||
| Phytochemical Name | Voacamine (PubChem CID: 11953931 ) | ||
| Anticancer drug Name | Doxorubicin (PubChem CID: 31703 ) | ||
| Structure of Phytochemical |
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2D
MOL
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| Structure of Anticancer Drug |
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| Pair Name | Voacamine, Doxorubicin | |||
| Disease Info | [ICD-11: 2B51] | Osteosarcoma | Investigative | |
| Biological Phenomena | Induction-->Autophagy | |||
| In Vitro Model | U2OS | Osteosarcoma | Homo sapiens (Human) | CVCL_0042 |
| U-2 OS R1 | Osteosarcoma | Homo sapiens (Human) | CVCL_T429 | |
| Result | Voacamine is capable of enhancing the cytotoxic effect of DOX on MDR cells by favouring a lethal autophagic process | |||
| No. | Title | Href |
|---|---|---|
| 1 | Autophagy-mediated chemosensitizing effect of the plant alkaloid voacamine on multidrug resistant cells. Toxicol In Vitro. 2007 Mar;21(2):197-203. doi: 10.1016/j.tiv.2006.09.007. | Click |
